International Journal of Ayurveda and Pharma Research 2023-01-24T06:46:43+08:00 Dr B Srinivasulu M.D (Ayu.) Open Journal Systems <div align="justify"> <p class="para1"><strong>International Journal of Ayurveda and Pharma Research (IJAPR)</strong>&nbsp;is an international peer reviewed Monthly open access Online and Print journal. The aim of the journal is to increase the impact of research in both academic and industry, with strong emphasis on quality and originality. The journal promotes to publish the articles in the field of&nbsp;<strong>Ayurveda, Siddha, Yoga, Naturopathy, Unani, Homeopathy and Allopathy</strong>&nbsp;systems of medicine and Pharmaceutical Sciences. Researchers may submit (1). Original Research Articles (2). Review articles (3). Book Reviews (4). Short Communications/ Research Letter (5). Case Report (6). Letter to the Editor/Correspondence.</p> </div> Comparative Analytical Study of Madana Shalatu (Unripen Fruit of Randia Dumetorum Lam) and Phalapippali (Processed Fruits of Randia Dumetorum Lam) - A Study of Abhava Pratinidhi Dravya 2023-01-24T06:46:21+08:00 Sunitha M P Nischal P <p><em>Vamana</em> is the <em>Agrya karma</em> for <em>Kaphaja vikaras</em>. <em>Madanaphala - Randia dumetorum</em> Lam is the drug of choice for <em>Vamana karma</em> because of its property – <em>Anapayitwat </em>(without untoward effect). Specific collection method, season and processing is required to get <em>Phalapippali</em> to possess above quality. <em>Madana shalatu</em>– Unripen fruits of <em>Madanaphala</em> is an <em>Abhavapratinidhi dravya</em> mentioned in <em>Sushrutha Samhita</em> and <em>Ashtanga Hrudaya</em> which does not require this processing- <em>Samskara</em>. So, in the present study comparative qualitative and quantitative physicochemical and phytochemical analysis of the <em>Madana Shalatu</em>, <em>Pakwa Madanaphala</em> &nbsp;Ripen fruit of <em>Madanaphala</em> and <em>Madanaphala Pippali</em>– Processed fruits of <em>Madanaphala</em> has been carried out. <strong>Aim</strong>: 1. Pharmacognostic, Physicochemical and Phytochemical analysis of <em>Madana Shalatu</em>, <em>Pakwa Madanaphala</em>, <em>Madanaphala Pippali</em>. 2. Comparative qualitative and quantitative phytochemical analysis of <em>Madana Shalatu</em>, <em>Pakwa Madanaphala</em>, <em>Madanaphala Pippali</em>. <strong>Method</strong>: 1. Pharmacognostic study – Macroscopic study and Microscopic study. 2. Preliminary physico chemical analysis. 3. Qualitative phyto chemical evaluation of aqueous and alcoholic extracts of the test drugs. 4. Quantitative analysis– UV Spectrophotometry. <strong>Result</strong>: Microscopic study, qualitative phyto chemical evaluation of all test drugs did not showed much differences. In total saponin estimation by UV Spectrophotometry of methanol and Water extract of ripen processed fruits of Randia, Ripen fruits of Randia and Unripen fruits of Randia is found to contain 73.71, 83.23, 71.35 and 72.62, 92.44, 75.25µg DE/mL of Saponin content respectively. <strong>Conclusion</strong>: Quantity of Saponin which is the main active principle in <em>Randia Dumetorum</em> responsible for <em>Vamana Karma</em> was similar in the <em>Madana Shalatu</em> and in <em>Phala Pippali</em>, whereas it was highest in <em>Pakwa Madanaphala</em>, thus it may be used like <em>Phala Pippali</em> without any laborious process of <em>Samskara</em>. Further Toxicity studies and clinical trials are required to prove its safety and efficacy in humans. &nbsp;</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research Added Effect of Pratimarsha Nasya with Ksheerabala Taila (14 Aavartita) over Selected Yoga Techniques in Insomnia 2023-01-24T06:46:01+08:00 Vrinda V V K Sunitha Sajitha Bhadran <p>Insomnia is a prevalent psycho physiological sleeping disorder, included in the International Classification of Sleep Disorders-2 (ICSD-2). By definition insomnia is a difficulty in initiating or maintaining sleep, or both or the perception of a poor quality sleep. Insomnia leads to various social, interpersonal and occupational impairments. Clinical studies have proven that <em>Yoga</em> is effective in insomnia. Present study was to find out the added effect of <em>Pratimarsha</em> <em>nasya</em> with <em>Ksheerabala</em> <em>taila</em> (14 <em>Aavartita</em>) over selected <em>Yoga</em> techniques in relieving insomnia. As per <em>Acharya</em> Susrutha in <em>Chikitsa</em> <em>Sthana</em>, doing <em>Pratimarsha</em> <em>nasya</em> daily during evening hours (<em>Sayamkala</em>) renders <em>Sukhanidraprabhodanam</em>. A pre-post interventional study was performed in 40 participants both male and female, satisfying the inclusion and exclusion criteria. Out of 40 participants, 20 each were randomly allocated to Group I and Group II. In Group I, <em>Pratimarsha</em> <em>nasya</em> using <em>Ksheerabala</em> <em>taila</em> (14 <em>Aavartita</em>) was administered 1ml in each nostril at evening time along with the practice of selected <em>yoga</em> techniques during morning hours. In Group II, only selected <em>Yoga</em> techniques were advised. The study period was for 30 days. The pre &amp; post changes in mean score value was assessed using Pittsburgh Sleep Quality Index (PSQI) score. The data was analyzed using unpaired t test, and was statistically significant with a p value ≤0.01. Thus the added effect of <em>Pratimarsha</em> <em>nasya</em> with <em>Ksheerabala</em> <em>taila</em> (14 <em>Aavrtita</em>) over selected <em>Yoga</em> techniques in insomnia is more effective than selected <em>Yoga</em> techniques alone.</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research Proximate Analysis, Phytochemical Screening and High Resolution Liquid Chromatography Mass Spectrophotometry Analysis of Essential Oils of Hedychium Coronarium J. Koenig, a Medicinal and Aromatic Plant 2023-01-24T06:46:18+08:00 Kamath Vaishali Dawda Himanshu <p>Medicinal plants have been used in all cultures as a source of medicine since ages. When parts of plants such as rhizomes, leaves or barks and other natural materials are used as drugs to treat illnesses, they are called crude drugs and the study of crude drugs is called pharmacognosy. Proximate analysis in plants gives valuable information and help to assess the quality of a crude drug. Beneficial effects of crude drugs are believed to be attributed to plant phytochemicals. <em>Hedychium coronarium</em> J. Koenig, a medicinal and aromatic plant of high value is an endangered and red-listed plant. The rhizome of this plant is used for the treatment of various diseases. Crude extracts prepared from the rhizomes show antibacterial and antifungal properties. Essential oils obtained from <em>Hedychium coronarium</em> are found to be rich in terpenes and used for bactericidal, fungicidal, medicinal and cosmetic applications. The present study assesses the quality of crude drugs prepared from this highly medicinal plant. Proximate analysis and phytochemical screening of rhizomes of <em>Hedychium coronarium,</em> which is frequently consumed as food and as medicine were carried out. Ash content was found to be low) when compared to the moisture content. The water extractive value was more than alcohol extractive. Preliminary tests carried out on phytochemicals revealed the presence of terpenoids and oils. High Resolution Liquid Chromatography Mass Spectrophotometry was carried to ascertain the different components of essential oils and revealed the presence of eucalyptol (1,8-cineole), caryophyllene oxide, camphor, linoleic acid, ricinin, phloroglucinol, 6-gingerol, carvone and arjungenin.</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research Effect of Snehadahana in the Management of Kadara - A Case Report 2023-01-24T06:46:38+08:00 Mayookha Madhusudanan K. Vasudeva Reddy B. K. Mugilmathi <p><em>Kadara</em> is a <em>Kshudra</em> <em>Roga</em>, first mentioned by <em>Acharya</em> <em>Sushruta</em>. It is a condition which causes extreme pain and discomfort to the affected person. <em>Kadara</em> may be correlated to Corn based on the causative factors, site of the swelling, clinical and other features. The incidence of corn in India is more than 10 million cases per year. The treatment modalities available at present in the modern science are the usage of corn caps, salicylic acid paints, cryotherapy and surgical excision. All theses modalities are associated with a high rate of recurrence. <em>Snehadahana</em> is mentioned as the line of management in <em>Kadara</em> after <em>Utkarthana</em> by all the <em>Acharyas</em>. <em>Acharya</em> <em>Bhoja</em> specifically mentions <em>Tila</em> <em>Thaila</em> as the <em>Sneha</em> <em>dravya</em> to be used for <em>Agnikarma</em>. In the present study, a 53 year old female patient, who visited the OPD of Sri Jayendra Saraswathi Ayurveda College and Hospital with a case of <em>Kadara,</em> was selected for <em>Snehadahana</em>. <em>Chedana</em> was done prior to <em>Snehadahana</em>. The procedure was carried out as 4 sittings, once a week, for a period of 4 weeks. Two follow ups were done at an interval of 14 days, after the fourth sitting of <em>Snehadahana</em>. There was complete healing of the wound and no recurrence seen until the follow up period.</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research Efficacy of Ayurvedic Medicines and Leech Therapy on Psoriasis, Complicated by Recurrent Cellulitis: A Case Report 2023-01-24T06:46:15+08:00 Jyoti Dhondiram Kshirsagar Sadik Khan <p>Cellulitis and Psoriasis are common bacterial skin infections. Psoriasis affects 1-3 percent of the world's population. According to Ayurveda, it is a curable disease, and leech therapy, a bloodletting method is considered the effective method in the treatment of psoriasis and cellulitis with no side effects. To evaluate the efficacy of leech therapy, Ayurvedic medicine, and lifestyle modification in the management of psoriasis complicated by recurrent cellulitis and other co-morbidities. This is a case report of a known diabetic and obese 39-year-old female patient. An Ayurvedic management plan and dietary modifications with leech application were administered to the patient. Leech application was done in five sessions with regular follow-ups. Leech therapy showed outstanding results in producing symptomatic relief for patients. It has helped the patient in reducing the condition of Psoriasis and Cellulitis with no common steroid therapy complications like weight gain and hyperglycemia. In this study, leech therapy showed excellent results in producing symptomatic relief for the patient. Leech therapy has a considerable anti-psoriatic and anticellulite impact without causing any toxicity or side effects.</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research Formulation and Evaluation of Herbal Neem Anti-Dandruff Shampoo 2023-01-24T06:46:43+08:00 Khandagale Sandip.S Supekar Amol.V Sarukh Vikram.S Bhasme Prajakta.S Shaikh Akiburrehman Shaikh Uwes Shaikh Fardin <p>The purpose of this present research work was to formulate and evaluate anti-dandruff shampoo which was prepared from herbal plant <em>Neem</em> leaves and <em>Tulsi</em>. These two plants are major role in formulation of anti-dandruff shampoo with antimicrobial and anti-inflammatory activity. The dandruff is a common disorder which is caused by yeast over growth, there is a fungus which is lives in the scalp of peoples called Malassezia. When a shampoo used under prescribed condition removes skin debris and the dirt from the scalp. Various antifungal and antimicrobial agents or drugs are uses in the preparation of shampoos, which causes the various side effects like hair loss, scratching, discomfort. An attempt to formulate <em>Neem</em> anti-dandruff shampoo which is safer and healthier than other anti-dandruff shampoo’s who are based on the chemicals. Herbal anti-dandruff shampoo formulated by all the herbal ingredients <em>Neem</em> leaves extract as API and anti-dandruff activity, <em>Tulsi</em> leaves which have the anti-microbial activity, <em>Aloe vera</em> which has moisturizing effect etc. The formulated shampoo were passed through evaluation parameter such as visual inspection, foaming capacity pH, viscosity, consistency of foam, etc.</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research Pharmacognostical Study of Leaf of Hamsapadi (Adiantum Lunulatum) 2023-01-24T06:46:12+08:00 Kadam Manoj Ghorpade Abhishek <p>Pharmacognostical evaluation of leaves of <em>Adiantum lunulatum </em>is done for identification in field and for differentiation from other species of <em>Adiantum</em>. <strong>Methods</strong>: A detailed literary work of drug studied and its pharmacognostical, phytochemical and analytical study including powder microscopy and taste determination of leaves with suitable instruments. <strong>Results</strong>: Macroscopic evaluation reveals the pinnacles are half moon shaped, alternate, sub-opposite or opposite in apical portion of the frond, having lobes with minor incisions. In microscopic structure the two surfaces of pinna are covered by epidermis and epidermal cells are wavy in outline. The opening and closing of stomata will be regulated by guard cells, whereas there is absence of stomata on epidermis. The vascular cells are lined by an endodermal tissue. Transverse section of petiole showed that it is externally covered by an epidermis lined by cuticle on its outer wall which renders the petiole to be shining. Below the epidermis is a fairly thick hypodermis made up Sclerenchyma cells of 4-5 layers in thickness. They are dead cells compact in arrangement and look dark in colour. Powder microscopy of leaves reveals shows few Tracheids of the veins and the Parenchyma cells of the leaves. The Sori are very prominent structures occurring at the leaf margin, they are visible characteristically under the microscope. The Sori contain number of Sporangia each Sporangium is lined by cells with U shaped thickening having their outer wall thin in nature. <strong>Conclusion</strong>: This study will help in Authentication of <em>Hamspadi </em>plant.</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research Medicinal Uses of Poisonous Plant - A Brief Review 2023-01-24T06:46:29+08:00 Priyanka R. C. Tiwari Aditi Yadav Akshu Sharma Indermani <p>A poisonous plant is defined as a plant that when touched or ingested in sufficient quantity can be harmful or fatal. Many plants are harmful to people when consumed or through skin contact with plant chemicals. Poisonous medicinal herbs are used to treat a variety of illnesses, including diabetes, cancer, infection, and fungal growth. According to the review, numerous phytochemical components that have diuretic, purgative, laxative, anti-allergic, and other significant therapeutic effects have been identified from a variety of medicinal plants. If utilized appropriately, poison can be life-giving, calming to the three <em>Doshas</em>, encouraging, and regenerating. The poisonous plants categorized in <em>Visha</em> and <em>Upvisha</em> in Ayurveda texts.<em> Agadtantra </em>is an important branch of <em>Astanga </em>Ayurveda<em>. </em>Importance of this branch has been described in our <em>Vedas, </em>Epics<em>, </em>and<em> Samhita</em>. Proper description, classification, clinical features, and management of any kind of <em>Visha</em> has been described in this branch. Name of some poisonous plants are <em>Dhatura</em>, <em>Vatsanabha</em>, <em>Bhallataka, Bhanga, Kuchala, Vacha</em> and <em>Gunja</em> etc. <em>Shodhana</em> process is the only bridge between <em>Visha</em> and <em>Aushadhi</em>. <em>Shodhana</em> is the process by which physical, chemical and natural impurities are removed. It will intensify the potency, effectiveness of drug, nullify the toxicity. The aim of this review article is to provide a brief overview of the numerous medicinal uses of some poisonous plant.</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research Commentators View on Medicinal Plants of Sushrutokta Salsaradi Gana Regarding their Controversial Botanical Identity: A Review 2023-01-24T06:46:23+08:00 Patel Priyalkumari Pravinbhai Srivastava Rashmi Upadhyaya Ashwani Pandit Ram Deo <p><em>Sushruta Samhita</em> is one of the foundational literature included in <em>the Brihat traiye</em> literatures of Ayurveda. Out of 37 different<em> Ganas </em>mentioned in <em>Sutra Sthana </em>of<em> Sushruta Samhita, Dravya-sangrahaniya-adhyaya</em>; <em>Salsaradi-gana</em> is one of them in which 23 medicinal plants have been described<em>. </em>&nbsp;Classically <em>Salsaradi-gana</em> is clinically indicated for <em>Kushta </em>(skin diseases)<em>, Prameha </em>(diabetes mellitus), <em>Pandu </em>(anemia), and<em> Kapha-medo-vishoshana </em>(anti-hyperlipidaemic) disease. For this study, a review of the original commentary of <em>Acharya Dalhana </em>and<em> Acharya haranchandra </em>on<em> Sushruta Samhita</em> and the scientific research papers published on the medicinal plants listed in the <em>Salsaradi-gana of Sushruta Samhita</em> in indexed journals is done. Out of 23 medicinal plants mentioned 8 plants have controversial identification. The controversy in the identification of these medicinal plants is seen directly affecting the pharmacological action and clinical efficacy. Those 8 plants’ controversial identity is cleared with the establishment of a genuine plant for each of the plants through scientific and classical justification. &nbsp;&nbsp;</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research Review on Plants Used in Siddha Formulation Vatha Siletpana Sura Kudineer for the Management of Viral Fever 2023-01-24T06:46:35+08:00 Vidhya Milano Prasad <p>Siddhars said about various diseases and the treatment methods with herbs, minerals and animal products. In Siddha literatures viral fevers can be compared to <em>Vatha Kapha Suram</em> and therefore decoction for this <em>Suram</em> is taken from classical Siddha text book and the ingredients are searched for pharmacological activity and toxicity study from 118 published journal papers from Pubmed, Scopus, Google Scholar, Research Gate and Science Direct. Collected data is entered in MS excel and analysed using RFC score. All together there are 51 pharmacological activities are published for these nine ingredients. In which Anti-inflammatory has RFC=1, other properties like antipyretic, anti-tussive, bronchodialator, anti-asthmatic, analgesic, neuro-regenerative, neuroprotective, anti-diarrhoeal, anti-emetic, neuroprotective, analgesic, sedative has more than 0.55 RFC score. More than this cardioprotective, renoprotective, hepatoprotective, and other protective properties are present in more than 50% of ingredients. In toxicity studies no toxic effects are seen in <em>in vivo </em>studies for the ingredients The <em>Suvai, Thanmai, Pirivu</em>, in Siddha aspect, of these ingredients can highly reduces <em>Vatha</em> and <em>Kapha</em> disorders. Therefore, the decoction shows significant pharmacological activity for the sign and symptoms of viral infections.</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research Yogasanas in Spasmodic Dysmenorrhoea w.s.r to Udavartha Yonivyapath 2023-01-24T06:46:40+08:00 Anisha A <p>Many women are familiar with the experience of spasmodic dysmenorrhoea, one of the commonest gynaecological conditions that affects the quality of life of many in their reproductive years. This condition manifested as painful menstruation, is the most frequently encountered gynaecological complaint and it can be included under <em>Udavartha yonivyapat</em>, caused by <em>Apanavata vaigunya</em> described in Ayurvedic classics. This situation not only has a significant effect on quality of life and personal health but also resulting in loss of work hours and depression. Scholastic backwardness and work absenteeism as a result of dysmenorrhoea is common nowadays. Most of the medical therapies for painful periods like analgesics, antispasmodics, NSAID, and anti-prostaglandins are having many side effects. Hormonal and surgical therapies are also not advisable to all type of patients, especially teenagers as it may harm their future reproductive capacity. Here comes the importance of <em>Yoga</em>, which provides good approach to treat primary dysmenorrhea.<em> Yoga asanas </em>helps in stretching muscles of pelvic cavity and increases the blood circulation to the pelvic organs and also helps to neutralize <em>Apana vayu</em>, which help in normal menstrual flow. The practice of <em>Asanas</em> has a beneficial impact on the whole body systems and helps in relaxation of both body and mind. This study is undertaken to find out the <em>Yogasanas</em> having pain relieving capacity in spasmodic dysmenorrhoea as it doesn’t cause any side effects but improve the quality of life. A thorough literary survey was done in <em>Yogic</em> classics especially <em>Asanas </em>for women’s health, <em>Asanas</em> for reproductive health and tried to compile the <em>Asanas</em> together having the pain relieving capacity in primary dysmenorrhoea.</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research Pharmacological Basis of Similia Similibus Curantur and the Nature of Homeopathic Materia Medica 2023-01-24T06:46:31+08:00 Rajaganapathy Lingeswaran Jayakumar Mohan <p>Similia Similibus Curantur is also called the law of similars. That is, when a drug produces pathological/pathogenic symptoms in healthy individual means, the same drug can relieve similar kinds of symptoms in individuals with the disease. The biological, pharmacological and toxicological action of capsaicin alkaloids is a perfect example to explain the Similia Similibus Curantur principle. Most of the drugs in homoeopathic materia medica contain toxicological, pharmacological, drug-proving, and traditional use-related symptoms and indications. Abnormal sensations and symptoms of the disease are caused by the involvement of a specific receptor or molecular pathway and gene functions. These receptors or molecules may be stimulated or suppressed by environmental, natural or artificial agents. In such conditions, the administration of specific homoeopathic medicine having a similar kind of affinity towards the particular receptors or molecules involved in the disease process leads to modulation of such receptor or molecular pathways (e.g., desensitization, sensitization, inhibition). These kinds of actions cause the betterment of symptoms or curative effects. So<strong> “</strong>Similia similibus curanter” can be understood as a similar receptor or molecular pathway involved in both drug molecules biological/ pharmacological and toxicological action and disease pathogenesis". The selection of medicine is by comparing the similarity between the receptor or molecular pathway in disease pathogenesis and drug pathogenesis. To avoid unwanted aggravations or side effects while using mother tinctures or solutions, administer them less than their physiological dose. The theory of the pharmacological basis of Similia Similia Curantur creates a rational method to apply this Similia Principle. Based on this theory, there is a possibility of discovering Novel drugs in the future that acts and gives a cure in similia similibus curantur way.</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research Lasunadi Agada in Lootha Visha Chikitsa - A Review 2023-01-24T06:46:09+08:00 Haritha M Ravikrishna S Sreejith K Chaithra S. Hebbar <p>Agadatantra had a golden time period in Kerala, and was known in the name of <em>Visha</em> <em>chikitsa</em>. There were excellent <em>Visha vaidhyas</em> who used to treat extreme venomous conditions and even predict the condition of patient just through the <em>Dootha lakshana</em>. As a part of these practices, there were numerous textbooks on <em>Visha chikitsa</em> with unique and exclusive Yogas. Some of the books got maintained, and many got ruined. Among those only few practices are still in use in the management if <em>Visha</em> and still many are untouched. <em>Prayoga samucchaya</em> is a well-known traditional <em>Keraleeya Visha chikitsa</em> textbook written by renowned King <em>Kochunni thamburan</em>, which explains the concepts of <em>Visha</em> and its detail management. <em>Lootha visha</em> is a most frequent and important clinical condition that which a physician encounters in their daily practice. It has got importance in all the time, as its manifestation is in such a way that improper handling of the case may worsen the presentation. There many <em>Agada yogas</em> mentioned in the management of <em>Lootha visha</em>. <em>Lasunadi Agada</em> is a simple yoga explained in <em>Prayoga samucchaya</em>, which contains only 6 drugs, explained in the context of <em>Lootha samanya chikitsa</em> as <em>Pana</em> and <em>Nasya</em>. Presently this yoga is practicing in the name of <em>Lasunadi gulika</em>. So this paper is an attempt to review on the formulation <em>Lasunadi Agada</em>.</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research Pregnancy-Induced Hypertension - Ayurvedic Understanding 2023-01-24T06:46:26+08:00 Lijima C Laxmipriya Dei <p>Pregnancy-induced hypertensive disorders are included among the most common medical complications of pregnancy with an incidence of 5–10%. Hypertension that develops as a direct result of gravid state is referred to as ‘pregnancy-induced hypertension’. The timely management of pregnancy complicated with hypertensive disorders is significant, otherwise it can lead to adverse fetal, neonatal and maternal outcomes. The basic pathology in pre-eclampsia, one of the types of hypertensive disorders is endothelial dysfunction and intense vasospasm due to abnormal placentation compromising blood flow to the foetoplacental unit. There is no direct reference of pregnancy-induced hypertension in Ayurveda classics, but the manifested symptoms can be explained within the purview of Ayurveda. Abnormality in placentation can be considered as impairment in the normal functioning of <em>Vata dosha</em> and when the pathology progresses further; <em>Kapha, Pitta</em> also play their own roles. In a woman with or without a previous history of pre-eclampsia, intervention should begin from pre-conceptional period. Planned pregnancy after pre-conceptional care followed by <em>Garbhini paricharya</em> along with the use of <em>Garbhasthapaka dravya</em>, <em>Rasayana dravya, Masanumasika Garbhasravahara dravya</em> can play significant roles in the prevention as well as management of pregnancy-induced hypertension thus improving the maternal and foetal outcomes.</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research A Review on Krishna Mrittika: A Part of Panchbhuatic Chikitsa of Ayurveda 2023-01-24T06:46:07+08:00 Riyanka Kumari Azara Qureshi <p><em>Ayurveda</em> the ancient traditional system of Indian medicine has two basic principles <em>Tridosha</em> And <em>Panchbhuatic Chikitsa</em> <em>Siddhant</em>. The elements of nature Earth, Water, Space, Fire and Air. All these elements are linked to the possibility of human life on Earth, and also contain compounds, minerals and nutrients that can improve our health. <em>Krishna</em> <em>Mrittika</em> is one of the most important elements of these and contains a lot of vital nutrients essential for the human body. The <em>Acharyas</em> told that <em>Krishna</em> <em>Mrittika</em> has <em>Shothahar</em> and <em>Shoolhar</em> <em>Gunas</em>. <em>Krishna</em> <em>Mrittika</em> can expel toxins from human body therefore is very useful in therapeutic and preventing many diseases. Ayurveda recommends <em>Krishna Mrittika</em> <em>Chikitsa</em> as a specialized therapy for good management of diseases. It is very Economic and effective also. It can be make easy methods. Its black colour absorbs all the colours of sun and According to the disease, affects the body organ. Solid and heavy human organs in the body are related to the <em>Prithavi Mahaboot</em>. As mentioned in <em>Atharvaveda</em> (12/1/6) that <em>Prithavi</em> detains lots of essential minerals, nutrients in it And by these minerals <em>Prithavi</em> nourishes the human Beings. This article, explaining how to use <em>Krishna</em> <em>Mrittika</em> as a therapeutic properties.</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research A Review Literature of Netra Swasthya Upakrama 2023-01-24T06:46:04+08:00 Pawase Shamli Shailendrakumar <p><em>Shalakyatantra </em>is one of the important branches of Ayurveda dealing with diseases and treatment of organs situated above the clavicle. As it deals with sense organs it is a highly specialized one. One should always make all sincere efforts to protect the eyes and treat eye diseases as it is one of the important sense organs. Ayurvedic literature gives equal importance to the prevention of disease with a cure. <em>Acharyas </em>have explained various regimens and protocols for a healthy life in <em>Dincharya</em> (daily routine) and <em>Rutucharya </em>(seasonal routine). Some of these regimens can be considered to be designed especially for the well-being of eyes like <em>Anjana, Nasya</em>, etc. These therapeutic procedures are useful if done scientifically and followed the protocol. Sushruta has mentioned 76 eye diseases out of which treatable diseases are treated with systemic as well as local treatment. <em>Kriyakalpa </em>is one of the local treatments. Various therapeutic procedures which are formulated with different drugs and different routes of drug administration according to <em>Dosh</em>, <em>Satmya</em>, and <em>Kal</em> have been explained to avoid the diseased condition. Being a local therapeutic procedure, fast action and penetration of drugs through ocular tissue raises the importance of <em>Kriyakalpa </em>in ocular diseases. Likewise, various regimens explained in <em>Dinacharya</em> and <em>Rutucharya</em> are important to maintain ocular health to avoid ocular diseases.</p> 2023-01-15T00:00:00+08:00 Copyright (c) 2023 International Journal of Ayurveda and Pharma Research