@article{B. Bhagwat_S Kadam_Hivarale_2017, title={THE ACCELERATED STABILITY STUDY OF CONSTALAX CHURNA- AN AYURVEDIC FORMULATION}, volume={5}, url={https://www.ijapr.in/index.php/ijapr/article/view/725}, abstractNote={<p><em>Constalax churna</em>, greenish brown powder with characteristic odor and bitter salty taste was evaluated for its stability, as per ICH guidelines Q1A (R2) at accelerated conditions (Temperature: 40 °C ± 2, Relative Humidity : 75% ± 5). The real time stability is estimated at temperature: 25 °C ± 2 &amp;relative humidity 60% ± 5.The study sample was observed for changes in different parameters like physico-chemical, organoleptic and microbial load for 6 month under accelerated conditions and for real time stability study observed for one year. Real time stability was comparatively estimated to evaluate actual degradation rate of <em>Constalax Churna </em>with respect to accelerated conditions. Up to six months of storage at accelerated condition, no change was observed in organoleptic parameters like colour, odour and taste of <em>Constalax Churna</em>. Changes in of different physico-chemical parameters were taken into account to evaluate intercept and slope. Extrapolated shelf life of <em>Constalax Churna was</em> calculated with 10% degradation rate from physico-chemical parameters at accelerated condition 40 °C ± 2 and 75% ± 5 RH. The present evaluation supports that the <em>Constalax Churna </em>was appropriate at accelerated condition up to 6 month storage. From this accelerated stability study it could be extrapolated that shelf life of <em>Constalax Churna </em>is 25.42 months (2.11years) for climatic zone I &amp; II countries. Real time stability data of <em>Constalax Churna </em>showed very good stability up to 2 years.</p&gt;}, number={7}, journal={International Journal of Ayurveda and Pharma Research}, author={B. Bhagwat, Gajanan and S Kadam, *Swapna and Hivarale, Madhuri}, year={2017}, month={Aug.} }