@article{Sarada_Kanchnara P_Madhavi P_Krishna_Kiran V_Anu_Sushmita Priyadarshini_Rinku_Seema_Subhashree_Srikanth_M M_K S_2015, title={THE MANAGEMENT OF PRIMARY DYSMENORRHOEA (KASHTARTAVA) - A PROSPECTIVE MULTICENTRIC OPEN OBSERVATIONAL STUDY}, volume={3}, url={https://www.ijapr.in/index.php/ijapr/article/view/108}, abstractNote={<p><strong>Objective: </strong>To evaluate the clinical usefulness of <em>Rajahpravartini</em> <em>vati</em> in the management of primary dysmenorrhoea (<em>Kashtartava</em>) and changes in the quality of life of the subjects.</p> <p><strong>Study design:</strong> A multi-centric prospective single arm observational study.</p> <p><strong>Setting and participants:</strong> 359 subjects aged between 16 - 35 years suffering from painful menstruation at least for three consecutive regular menstrual cycles were included in the study.</p> <p><strong>Intervention: </strong><em>Rajahpravartini Vati</em> a classical Ayurvedic formulation was administered 250 mg b.d. with lukewarm water for 90 days followed by subsequent 90 days without intervention.</p> <p><strong>Outcome measures:</strong> The management of menstrual pain assessing by 10 points Visual Analogue Scale and improvement in the quality of life using SF-36 (RAND) questionnaire.</p> <p><strong>Results:</strong> The mean VAS score of pain at baseline was 6.94±1.98, decreasing to 1.7±2.22 at 90<sup>th</sup> day which further decreased and maintained to 1.24±1.9 up to 180<sup>th</sup> day. Associated symptoms like nausea, vomiting, constipation, giddiness, breast tenderness, diarrhea, headache and fainting were completely relieved. The improvements of quality of life in 8 domains viz. pain, general health, physical functioning, social functioning, emotional wellbeing, energy/fatigue, limitation due to physical health and emotional problems at the end of 90<sup>th</sup> day of intervention was also significant (p&lt;0.001) in comparison to baseline. No adverse event occurred during the treatment period.</p> <p><strong>Conclusion:</strong> <em>Rajahpravartini Vati</em> has shown a positive role for the treatment of dysmenorrhoea and to improve the quality of life of the subjects.</p&gt;}, number={7}, journal={International Journal of Ayurveda and Pharma Research}, author={Sarada, Ota and Kanchnara P, Devi and Madhavi P, Kutty and Krishna, Kumari and Kiran V, Kale and Anu, Bhatnagar and Sushmita Priyadarshini, Ota and Rinku, Tomar and Seema, Jain and Subhashree, M N and Srikanth, N and M M, Padhi and K S, Dhiman}, year={2015}, month={Dec.} }